Eosinophilic Esophagitis, commonly referred to as EoE, is a chronic immune system disease that affects the esophagus, the tube that allows food to travel from the mouth to the stomach. This condition can make swallowing difficult (a condition known as dysphagia) and can sometimes lead to food becoming lodged in the esophagus (known as food impaction).
When Food Becomes a Problem
Imagine sitting down for a meal and suddenly your food feels stuck in your throat, not blocking the airway but lodged in the esophagus. This scenario typically requires an emergency room visit, where a gastroenterologist performs an endoscopy to remove the obstruction.
Diagnosis and the Role of Allergy Specialists
The onset of swallowing difficulties can be gradual over months or appear suddenly. During an endoscopy, a gastroenterologist may take biopsies to check for elevated eosinophils in the esophagus, a white blood cell that signals EoE when found in high levels.
Research and New Treatments
Our team is deeply involved in the latest research exploring innovative treatments for EoE. We are currently participating in studies investigating the effectiveness of medications like Fluticasone and Dupilumab. Recent data from these studies suggest that treatment with Dupilumab can help restore the esophageal environment to a state similar to that of individuals without EoE.
Treatment Options for EoE
Treatment strategies for EoE vary greatly depending on the individual’s condition and response to therapy. Some patients find relief through specific diets formulated with the help of their allergist. Others may benefit from medications typically used to treat acid reflux, while some may require more potent treatments like steroids.
Involve Yourself or Discover More
If you or someone you know is struggling with symptoms of EoE or is interested in participating in research to find new treatments, contact our clinic.
In data presented at UEG, investigators find post-dupilumab transcriptome closely resembles the transcriptome of a healthy control group. https://www.hcplive.com/view/dupilumab-eosinophilic-esophagitis